I rewatched Anacondas: The Hunt for the Blood Orchid last night. (Shut up.) IMDb.com says that one of the leads, the yummy Johnny Messner, is on The O.C. as Lance Baldwin. I've never watched that show. But he's also on an early episode of Angel, as Kevin in "Lonely Hearts" (#1.2). It could be a one-minute walk-on, but I'll have to rewatch.
Ironically, I bailed on "Hell Bound" (the Spikecentric S5 Angel ep) to rewatch Anacondas. And even paid for the movie again, as I discovered I'd only recorded fuzz the first time. My Spike issues with S5 are apparently big and hairy and fanged.